A fluidic chip, from prototype to pre-series

For Analis, Sirris is developing prototype tooling for the injection of fluidic chips that include micro-details.

With over 25 years of experience in electrophoresis and capillary electrophoresis, Analis develops and markets kits for in-vitro diagnosis, the life sciences and analytic applications.

The company, which was looking to develop its own consumables for one of its analysis systems, called upon Sirris to develop a fluidic chip. The chip includes a capillary and is equipped with a fibre optic reading window.

Sirris initially provided several machined prototypes of the chip in the form of a multiple-part assembly. This enabled Analis to test various reading window dimensions and to validate the chip's design on its test bench. Thanks to its skills in micromachining, Sirris was able to provide parts with micro-details as small as 50µm in the window.

After validating geometry, Sirris designed and developed a prototype injection tool to produce a true material pre-series of the chip in an aim to reunite its functionalities within one single part and to validate the implementation technique for future industrialisation.

For injection, digital simulations were conducted to validate the mould. After adjustment, a pre-series of test parts was then moulded in ABS.

Relying on its microinjection skills, Sirris was able to produce the necessary micro-details on the mould, and to replicate them on injected parts.
Other difficulties such as capillary encapsulation were also overcome.

Sirris also developed associated parts such as a set of polypropylene injected multiwells. In order to improve the precision of analyses impacted by solution evaporation, Analis called once more upon Sirris for the design of a capping system for its system's wells.

Other projects between Sirris and Analis are currently underway, for which the R&D division is particularly active.